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A 21-year-old has crashed his motorbike into a telegraph pole and has serious leg and lung injuries. And a patient with paralysing locked-in syndrome is struggling to breathe after his breathing tube becomes dislodged.

Twelve famous faces, including performers Brian and Lucy Conley and `Strictly' pros Amy Dowden and Carlos Gu, go on the run in aid of Stand Up To Cancer, pursued by Chief Ray Howard and his army of Hunters.

Two of the fugitives drop in on a celebrity colleague while another pair make a bold move going on live TV. And two celebs are cracking jokes in Brighton, but will the Hunters have the last laugh?

Gordon heads to country music's spiritual home, Nashville, Tennessee, but his visit begins on a sour note at Chappy's Cajun restaurant. Chef John 'Chappy' Chapman's careless methods have hurt his local reputation.

The recorded testimonies of those who met and knew Adolf Hitler reveal the truth about the man behind the worst crimes in history. Hitler's closest friends and enablers recount his first days in politics.

Border Force officers are on the hunt for illegal meat being smuggled into Britain, the engineers face their biggest job of the year, and police officers are on a stake-out for a potential criminal.

Paul and Amy Wilkinson build a lakeside home in Lincolnshire with five circular timber buildings linked by walkways, but Paul's health suffers as he struggles to finish the build a year.

Kirstie and Phil look back on their favourite working from home transformations, from a cluttered terrace in Northampton to a three-bed semi in Waterbeach.

Colin Murray, Rachel Riley and Susie Dent host, with Ade Adepitan in Dictionary Corner, as contestants race against the clock to pit their wits against vowels, consonants and numbers.

When Doug forgets Carrie's 30th birthday, he has to scramble to put together a romantic evening. Will Doug's luck be in and everything fall into place?

Arthur attends a party and meets a woman, Mary, and the two begin a love affair. Meanwhile, Carrie is waiting for Doug at a restaurant.

When Carrie gets a ticket for reckless driving, she tries to get out of it by chatting the cop up, though this results in him asking her out. How far will she go to avoid a fine?

When Michael stays home from school for two days in a row, Ray suspects he simply has homework he hasn't finished.

Debra and Ray are annoyed at the over-the-top affection which Robert and Amy are expressing towards each other. To make matters worse, Robert and Amy dole out some marriage advice to Ray, and give Debra a book on how to maintain a good relationship.

Debra persuades Ray to hire Gianni to do some DIY work in their kitchen, but they both soon regret it due to their friend's laziness.

On a quiet day at the radio station, Frasier tells a depressed caller about Eddie's recent run-in with the dog therapist.

Frasier and Niles' spontaneous gesture to share a table with two strangers (Lisa Darr, Megan Mullally) leads to a double date followed by a weekend getaway at a mountain cabin.

A pet parrot disrupts the dinner party Niles hosts for his new neighbours in a ritzy flat building.

Roz decides to complete a community service order she has been given at a retirement home. When all the patients she tends to pass on, she needs Frasier's reassurance that she is not the "angel of death".

After his son died, Leo's passion for his Italian restaurant in Texas faded, leading to poor food quality and service. Can Gordon re-ignite Leo's love for la dolce vita?

Channel 4's midday news summary.

Henry Cole and Simon O'Brien go to restore a Gothic style organ and a half-size snooker table in the south Wales workshop that sisters Carly and Holly have inherited from their dad.

Adam and Dave buy a bungalow to renovate in Glossop. Between them, they have building experience and bags of enthusiasm. They try to give this tired house a new lease of life.

Colin Murray, Rachel Riley and Susie Dent host, with Ade Adepitan in Dictionary Corner, as contestants race against the clock to pit their wits against vowels, consonants and numbers.

Craig Rowe helps Bridget and Rob, who want to do something special for themselves by finding a property for relaxing breaks and plenty of winter sunshine. The couple have a £160,000 budget, and Craig shows them several great properties.

During a glorious Cotswolds summer at Chavenage House, James Lowsley-Williams starts to rescue a derelict and overgrown pond. And the restoration of Ashby Manor's Gunpowder Plot room becomes increasingly complex.

Sarah and George transform two enormous barns into a nightclub and a lounge for their wedding business. May and Guy race to renovate an uninviting terrace. And Terry and Ashley battle with nature, as they try to get their garden under control.

It's a picking paradise as Mike and Frank come across a huge 200,000-square-foot factory housing a private collection cultivated by Woody, the building's dumpster-diving owner.

Channel 4's flagship news programme. With sport and weather.

In West Sussex, Vogue and Luke help to salvage Penny's dream of a relaxing retirement near family, by the sea. Can she finally finish her long-overdue renovation and draw a line in the sand under it?

Matthew Daulby was fatally stabbed after a fight erupted on the street in Ormskirk. His killer fled the country, triggering an international manhunt driven by digital detective work.

An ex-detective and forensic experts re-open cold cases of unidentified bodies across the UK, starting with the complex story of a hero who vanished off the Norfolk coast in 1984 while on a family holiday.