RETRO é exibido principalmente nos Estados Unidos, com foco em programas de televisão de décadas passadas. O conteúdo do canal é fortemente baseado nos anos 1950 até os 1990, incluindo uma mistura de sitcoms clássicas, séries dramáticas e filmes antigos que foram ao ar originalmente nesses períodos. Alguns blocos de programação destacam apresentações musicais antigas, programas de variedades ou documentários culturais que refletem o entretenimento da época. A grade evita reality shows contemporâneos ou noticiários, apostando em reprises de séries e filmes sindicalizados que mantiveram presença na cultura pop americana. Quem sintoniza encontra atrações que foram exibidas originalmente em grandes redes de TV, geralmente apresentadas sem edição ou comentários modernos.

Para quem não tem TV a cabo, a RETRO está disponível em plataformas de streaming selecionadas que oferecem pacotes de TV ao vivo, embora a programação específica varie conforme o provedor. Guias de programação impressos em jornais locais ou bancos de dados online costumam mostrar a grade diária do canal, que repete certas séries em blocos temáticos. O canal não produz conteúdo

Guia de TV
Split Decisions
07:04 - 08:41
Split Decisions
Movie, Drama, Action
An Irish-American boxer (Craig Sheffer) turns pro with his father (Gene Hackman) for one fight, to avenge his slain boxer brother.
Crossworlds
08:41 - 10:13
Crossworlds
Movie, Science fiction, Comedy, Action
A magic crystal leads a college student (Josh Charles) and an adventurer (Rutger Hauer) on a surreal quest to save the world.
A Different Loyalty
10:13 - 11:59
A Different Loyalty
Movie, Drama
An expatriate (Sharon Stone) travels to the Soviet Union after her husband (Rupert Everett) is accused of being a double agent working for the KGB.
Iron Brothers
11:59 - 13:33
Iron Brothers
Movie, Action, Adventure
Fur trappers Abel and Henry Iron struggle to survive in the Rocky Mountains.
The Stranger
13:33 - 15:08
The Stranger
Movie, Thriller
Immediately following World War II, ex-Nazi Franz Kindler is living under a false identity as a teacher in a small Connecticut town, and has even married the headmaster's daughter as part of his cover. But when one of Kindler's old German associates arrives unexpectedly in town, bringing in his wake a sly federal investigator, Kindler resorts to desperate measures to preserve his secret.
Dust
15:08 - 17:13
Dust
Movie, Western, Drama
After falling in love with the same woman, two brothers (Joseph Fiennes, David Wenham) fight for opposing sides of a battle between Turks and Macedonians.
Beyond the Stars
17:13 - 18:46
Beyond the Stars
Movie, Drama
The son (Christian Slater) of a former NASA scientist (Robert Foxworth) befriends a fallen astronaut (Martin Sheen) changed for life by his moonwalk.
A Different Loyalty
18:46 - 20:32
A Different Loyalty
Movie, Drama
An expatriate (Sharon Stone) travels to the Soviet Union after her husband (Rupert Everett) is accused of being a double agent working for the KGB.
Crossworlds
20:32 - 22:04
Crossworlds
Movie, Science fiction, Comedy, Action
A magic crystal leads a college student (Josh Charles) and an adventurer (Rutger Hauer) on a surreal quest to save the world.
Split Decisions
22:04 - 23:41
Split Decisions
Movie, Drama, Action
An Irish-American boxer (Craig Sheffer) turns pro with his father (Gene Hackman) for one fight, to avenge his slain boxer brother.
Dust
23:41 - 01:46
Dust
Movie, Western, Drama
After falling in love with the same woman, two brothers (Joseph Fiennes, David Wenham) fight for opposing sides of a battle between Turks and Macedonians.